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Epiphora following chemotherapy with pemetrexed in patients with advanced non-small cell lung cancer
Yun Duk Jung, Sang Bin Lee, Yun Wha Jung, Jung Sub Song, In Sook Woo
Korean J Intern Med. 2017;32(5):923-925. Published online March 18, 2017
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Rheumatology
Ileocolonoscopic findings in patients with ankylosing spondylitis: a single center retrospective
study
Soo Min Ahn, Yong-Gil Kim, Seung-Hyeon Bae, Doo-Ho Lim, Seokchan Hong, Sang Hyoung Park, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2017;32(5):916-922. Published online August 11, 2017
Background/Aims: In some Western countries, up to 50% of patients with ankylosing spondylitis (AS) have subclinical gut inflammation. This study was conducted to evaluate the prevalence and severity of gut inflammation and to determine clinical factors associated with colonic inflammation in Korean ..
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Allergy
Korean version of the Cough Symptom Score: clinical utility and validity for chronic cough
Jae-Woo Kwon, Ji-Yong Moon, Sae-Hoon Kim, Woo-Jung Song, Min-Hye Kim, Min-Gyu Kang, Kyung-Hwan Lim, So-Hee Lee, Sang Min Lee, Jin Young Lee, Hyouk-Soo Kwon, Kyung-Mook Kim, Sang-Heon Kim, Sang-Hoon Kim, Jae-Won Jeong, Cheol-Woo Kim, Sang-Heon Cho, Byung-Jae Lee; Work Group for Chronic Cough, the Korean Academy of Asthma, Allergy and Clinical Immunology
Korean J Intern Med. 2017;32(5):910-915. Published online March 31, 2017
Background/Aims: The Cough Symptom Score (CSS) is a simple, useful tool for measuring cough severity. However, there is no standard Korean version of the CSS. We developed a Korean version of the CSS and evaluated its clinical utility and validity for assessing chronic cough severity.
Methods: The..
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Pulmonology
The activation of NLRP3-inflammsome by stimulation of diesel exhaust particles in lung tissues from emphysema model and RAW 264.7 cell line
Soo-Taek Uh, So My Koo, Yangki Kim, Kiup Kim, Sungwoo Park, An Soo Jang, Dojin Kim, Yong Hoon Kim, Choon-Sik Park
Korean J Intern Med. 2017;32(5):865-874. Published online August 18, 2017
Background/Aims: Diesel exhaust particles (DEPs) lead to elevation of reactive oxygen species, which can activate the nucleotide-binding oligomerization domain-like receptor (NLR) family members containing the pyrin domain 3 (NLRP3)-inf lammasome. In this study, we elucidated whether NLRP3 -inf lamm..
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Gastroenterology
Identification of distinctive clinical significance in hospitalized patients with endoscopic duodenal mucosal lesions
Yeji Han, Hye-Kyung Jung, Ji Young Chang, Chang Mo Moon, Seong-Eun Kim, Ki-Nam Shim, Sung-Ae Jung, Joo-Young Kim, Ji-Yun Bae, Sae-In Kim, Ji-Hyun Lee, Sanghui Park
Korean J Intern Med. 2017;32(5):827-835. Published online August 21, 2017
Background/Aims: Duodenitis is not infrequent finding in patient undergoing endoscopy. However, hospitalized patients have a higher incidence of secondary duodenal mucosal lesions that might be related with inflammatory bowel disease (IBD), cytomegalovirus (CMV) infection, tuberculosis, immunologic ..
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Pulmonology
Treatment of connective tissue disease-associated interstitial lung disease: the pulmonologist’s point of view
So-My Koo, Soo-Taek Uh
Korean J Intern Med. 2017;32(4):600-610. Published online June 30, 2017
Interstitial lung disease (ILD) occurs in 15% of patients with collagen vascular disease (CVD), referred to as connective tissue disease (CTD). Despite advances in management strategies, ILD continues to be a significant cause of mortality in patients with CVD-associated ILD (CTD-ILD). There is a la..
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Infectious diseases
The seroprevalence of Bartonella henselae in healthy adults in Korea
Hea Yoon Kwon, Jae Hyoung Im, Sun Myoung Lee, Ji Hyeon Baek, Areum Durey, Shin-Goo Park, Jae-Seung Kang, Jin-Soo Lee
Korean J Intern Med. 2017;32(3):530-535. Published online April 20, 2017
Background/Aims: Cat-scratch disease (CSD), caused by Bartonella henselae is one of the most common zoonosis. However, only several cases of B. henselae infection have been reported in Korea. This study investigated the seroprevalence of B. henselae in healthy adults and related..
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Cardiology
Fragmented QRS and abnormal creatine kinase-MB are predictors of coronary artery disease in patients with angina and normal electrocardiographys
Jung Joo Lee, Jae Hoon Lee, Jin Woo Jeong, Jun Young Chung
Korean J Intern Med. 2017;32(3):469-477. Published online April 17, 2017
Background/Aims: Patients with symptoms of coronary artery disease (CAD) often display normal tracings or only nonspecific changes on electrocardiography (ECG). The aim of this study was to explore strategic elements of the ECG and other potential factors that are predictive of CAD in this scenario...
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Features of electrocardiogram in patients with stenosis of the proximal right coronary artery
Moo Seong Koh, Jae Hoon Lee, Jin Woo Jeong, Jun Young Chung
Korean J Intern Med. 2017;32(2):277-285. Published online February 14, 2017
Background/Aims: Prediction of lesions of the proximal right coronary artery (pRCA) through electrocardiogram (ECG) is very important because pRCA occlusion has many complications and a high mortality rate, which has frequently been related with right ventricular infarction. The purpose of this stud..
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Gastroenterology
Decreased S100B expression in chronic liver diseases
Su Jung Baik, Tae Hun Kim, Kwon Yoo, Il Hwan Moon, Ju Young Choi, Kyu Won Chung, Dong Eun Song
Korean J Intern Med. 2017;32(2):269-276. Published online June 3, 2016
Background/Aims: Hepatic innervation in liver diseases is not fully understood. We here evaluated S100B expression as a marker of hepatic nerves in patients with various chronic liver diseases, topographically and semi-quantitatively.
Methods: Liver specimens were obtained from 70 subjects (three c..
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Endocrinology-metabolism
Linking resistin, inflammation, and cardiometabolic diseases
Hyeong Kyu Park, Mi Kyung Kwak, Hye Jeong Kim, Rexford S. Ahima
Korean J Intern Med. 2017;32(2):239-247. Published online February 16, 2017
Adipose tissue secretes a variety of bioactive substances that are associated with chronic inflammation, insulin resistance, and an increased risk of type 2 diabetes mellitus. While resistin was first known as an adipocyte-secreted hormone (adipokine) linked to obesity and insulin resistance in rode..
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Pulmonology
Diagnosis and treatment of cystic lung disease
Sanghoon Park, Eun Joo Lee
Korean J Intern Med. 2017;32(2):229-238. Published online February 28, 2017
Cystic lung disease (CLD) is a group of lung disorders characterized by the presence of multiple cysts, defined as air-filled lucencies or low-attenuating areas, bordered by a thin wall (usually < 2 mm). The recognition of CLDs has increased with the widespread use of computed tomography. This artic..
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Acute cor pulmonale due to pulmonary tumor thrombotic microangiopathy in two patients with breast cancer
Sung Young Moon, Kang Hoon Lee, Jong Sik Lee, Hyun Suk Yang, Hong Ghi Lee, Yo Han Cho, So Young Yoon
Korean J Intern Med. 2017;32(1):190-194. Published online February 3, 2016
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Endocrinology-metabolism
Application of photodynamic therapy in gastrointestinal disorders: an outdated or re-emerging technique?
Han Hee Lee, Myung-Gyu Choi, Tayyaba Hasan
Korean J Intern Med. 2017;32(1):1-10. Published online January 1, 2017
Photodynamic therapy (PDT) is a promising therapeutic modality that involves the administration of a photosensitizer followed by local illumination with a specific wavelength of light in the presence of oxygen. PDT is minimally invasive, has high selectivity for cancer, and has good patient complian..
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Pulmonary graft-versus-host disease after autologous hematopoietic stem cell transplantation
Sue In Choi, Eun Joo Lee, Dong Oh Kang, Sang Yeub Lee, Kwang Ho In, Han-Kyeom Kim, Sanghoon Park
Korean J Intern Med. 2016;31(6):1181-1183. Published online December 23, 2015
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Nephrology
Prevalence of chronic kidney disease defined by using CKD-EPI equation and albumin-to-creatinine ratio in the Korean adult population
Eunhee Ji, Yon Su Kim
Korean J Intern Med. 2016;31(6):1120-1130. Published online March 25, 2016
Background/Aims: An updated chronic kidney disease (CKD) definition and classification were proposed by Kidney Disease: Improving Global Outcomes (KDIGO), with adoption of a new equation to estimate glomerular filtration rate (GFR) and albuminuria to evaluate kidney structural damage. This study was..
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Endocrinology-metabolism
Elevated lipoprotein(a) levels predict cardiovascular disease in type 2 diabetes mellitus: a 10-year prospective cohort study
Tae-Seok Lim, Jae-Seung Yun, Seon-Ah Cha, Ki-Ho Song, Ki-Dong Yoo, Yu-Bae Ahn, Yong-Moon Park, Seung-Hyun Ko
Korean J Intern Med. 2016;31(6):1110-1119. Published online October 18, 2016
Background/Aims: Elevated lipoprotein(a) (Lp[a]) level is known to be a risk factor for cardiovascular disease (CVD). However, the data that has been reported on the association between the Lp(a) level and CVD in type 2 diabetes has been limited and incoherent. The aim of this study was to investiga..
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Cardiology
Blood count parameters can predict the severity of coronary artery disease
Hilal Bektas Uysal, Bekir Dağlı, Cağdaş Akgüllü, Mücahit Avcil, Cemil Zencir, Mediha Ayhan, Hulki Meltem Sönmez
Korean J Intern Med. 2016;31(6):1093-1100. Published online April 7, 2016
Background/Aims: Because of the inflammatory nature of coronary artery disease (CAD), both platelets and white blood cells have been investigated for years. The aim of this study was to investigate the relationships between some prominently hematologic blood count parameters (mean platelet volume [M..
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Two-year clinical outcomes in stable angina and acute coronary syndrome after percutaneous coronary intervention of left main coronary artery disease
[corrected-article]
Dae Young Hyun, Myung Ho Jeong, Doo Sun Sim, Yun Ah Jeong, Kyung Hoon Cho, Min Chul Kim, Hyun Kuk Kim, Hae Chang Jeong, Keun Ho Park, Young Joon Hong, Jun Han Kim, Youngkeun Ahn, Jung Chaee Kang
Korean J Intern Med. 2016;31(6):1084-1092. Published online October 18, 2016
Background/Aims: This study appraised the long term clinical outcomes of patients treated with percutaneous coronary intervention (PCI) for unprotected left main coronary artery (ULMCA) disease. There are limited data regarding long-term clinical outcomes after PCI for ULMCA disease.
Methods: From..
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Mean platelet volume: a potential biomarker of the risk and prognosis of heart disease
Dong-Hyun Choi, Seong-Ho Kang, Heesang Song
Korean J Intern Med. 2016;31(6):1009-1017. Published online October 24, 2016
Platelets are essential for progression of atherosclerotic lesions, plaque destabilization, and thrombosis. They secrete and express many substances that are crucial mediators of coagulation, inflammation, and atherosclerosis. Mean platelet volume (MPV) is a precise measure of platelet size, and is ..
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